Blood and Marrow Transplantation (BMT)
Improving Outcomes Through Comprehensive, Compassionate Care and Research
Transforming Care for Our Sickest Kids: Meet Dr. Auletta
Blood and Marrow Transplantation (BMT)
At Nationwide Children’s, The Blood and Marrow Transplant (BMT) team never stops searching for the best outcome with the least impact. You and your child will not be alone as we develop the best treatment plan for your child.
All BMT patients are offered participation in clinical trials, and we collaborate closely with Oncology and Hematology so you can be assured that your child’s care is informed by experts in each area.
We perform stem cell transplantation from all cell sources including:
- Sibling Allogeneic
- Matched Unrelated
- Cord Blood -Matched Related and Unrelated
- Haplo Related
The Pediatric Blood and Marrow Transplant (BMT) Program at Nationwide Children’s Hospital is a National Marrow Donor Program (NMDP) Transplant Center and is accredited by the Foundation for Accreditation of Cellular Therapy (FACT).
Dr. Auletta is working hard to discover new ways to fight cancer and other diseases in some of our sickest kids. His focus is cell-based immunotherapy - essentially, leveraging and bolstering the body's natural ability to fight cancer. Dr. Auletta comes to work every day with the hopes of helping our families through some of the most difficult moments they may ever have.
Jeffery Auletta, MD, is the Director of the Blood and Marrow Transplant (BMT) Program and the Host Defense and Immunocompromised Infectious Diseases (HD) Program at Nationwide Children's Hospital.
The Bone Marrow Transplant (BMT) Clinic provides care to patients and families before and after transplant.
As an integral part of the care team, the Psychosocial Services Program is one of the most comprehensive in the country. We ensure patients and their families have every resource needed socially, emotionally and psychologically.
- AYA Oncology Program
- Genetic Counseling and Testing
- Fertility preservation
- Physical therapy
- Palliative care
- Radiation oncology
- Pain management
Learn more about current Blood and Marrow Transplant clinical trials at Nationwide Children's.
Resources for Families
Children requiring a bone marrow transplant are referred to a pediatric transplant center. Such centers have experience performing transplants and caring for children, adolescents and young adults after they receive a bone marrow transplant.
A bone marrow transplant involves taking those stem cells from a donor and putting them into a patient. The patient usually has received chemotherapy or radiation before receiving the donor stem cells.
For children with healthy immune systems, mold exposure from the environment is not dangerous. Some people who are sensitive to molds might develop allergy symptoms due to chronic exposure to high amounts of mold.
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The Pediatric Blood and Marrow Transplant Program at Nationwide Children’s Hospital offers a one-year BMT fellowship for qualified physicians who completed a basic 3-year program in pediatric hematology/oncology and who wish to pursue further training in pediatric blood and marrow transplantation.
Graduates will be competent in the use of transplantation and cellular therapy for the treatment of malignant or non-malignant diseases. Specifically, the program trains physicians in indications for transplant; pre-transplant patient evaluation; identification and selection of stem cell sources; use of donor registries; methodologies of HLA typing; marrow cryopreservation; management of ABO incompatible cell products; administration of high-dose chemotherapy; management of neutropenic fever; management of bacterial/viral/fungal diseases in immunocompromised patients, management of bleeding diathesis, diagnosis and management of regimen related toxicities, diagnosis and management of acute and chronic graft-versus-host disease, late complications of marrow transplantation; terminal care; as well as training in documentation and reporting for patients being treated on investigational trials.
Trainees gain experience in bone marrow harvest; stem cell apheresis; stem cell product infusions; and advanced cell processing techniques. Trainees are also encouraged to participate in protocol design and development and complete a clinical research project related to transplantation during the course of their training.
We offer a one-year Bone Marrow Transplant Fellowship for qualified physicians who wish to pursue further training in pediatric blood and marrow transplantation.
Meet Our Team
Behind every patient is a compassionate team of doctors, nurses, researchers, therapists, social workers and support staff, all focused on providing individualized care and support.
BMT School Services
School is one of the most important aspects in the life of a child or adolescent. After a bone marrow transplant your child will not attend school until immune recovery.
BMT At A Glance
The goal of the BMT Program is to provide comprehensive, compassionate care while advancing the field of hematopoietic cell transplantation through research that makes a difference in a patient’s life.
Well Connected: BMT at Nationwide Children's Hospital
As the pediatric affiliate of the NCI-designated OSUCCC-James, the BMT Program at Nationwide Children’s is connected to one of the premier adult cancer institutions in the country, thus enabling an unrivaled continuum of care.
BMT Translational Research
By integrating care, research and collaboration at all levels, we are able to elevate the patient’s opportunities for best outcomes and advance the field of BMT.
Immunotherapy is focused on harnessing and manipulating the natural ability of the immune system to fight cancers.
Host Defense Program
Our collaborative and comprehensive approach ensures that the unique needs of your patient will be reviewed and provided by fellowship-trained Host Defense Specialists, who are supported by an interdisciplinary team of experts in immunocompromised conditions.
Blood and Marrow Transplantation News
More Blood and Marrow Transplantation
Cellular Therapy - Deconstructing a Bone Marrow Transplant to Cure Cancer
Over the past 40 years, carefully combining chemotherapy, radiation therapy and surgery has brought the overall cure rate for childhood cancer to nearly 80 percent. However, for many cancers, these conventional therapies have reached a plateau.
Immunodeficiency and Infection: Who Is at Risk?
Certain conditions may cause a child to become immunocompromised. Some children are born with abnormal immune systems and have genetic conditions called primary immunodeficiency disorders like chronic granulomatous disease (CGD) or severe combined immunodeficiency (SCID).
Stem Cell Transplant: Who Can Benefit and Who Can Be the Donor?
A stem cell transplant is a treatment that involves infusing hematopoietic (blood-forming) stem cells from a donor into a recipient. The collection of infused stem cells is called the stem cell “graft.”